Alzheimers disease (AD)
Conditions
Interventions
Sponsors
the first hospital of hebei medical university
Eligibility
Sex/Gender
All
Age
55 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.right-handed patients aged 55-85 years; 2.at least 6 years of education; 3.probable Alzheimer’s dementia diagnosed by the 2011 National Institute on Aging AD (NIA-AA) guidelines; 4.Clinical Dementia Rating (CDR) score of 0.5;
Exclusion criteria
Exclusion criteria: 1.complications with other neurological diseases, structural brain abnormalities, or severe diseases of the heart, liver, lung, or kidney; 2.non-MRI compatible metallic implants, such as pacemakers , or cardiac stents; 3.currently taking benzodiazepines or having a history of drug abuse; 4.a diagnosis of major depressive disorder or other severe mental illness;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alzheimer's disease assessment scale-Cognitive; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neuropsychiatric inventory;Mini mental state examination;Digit span test;Clinical dementia rating scale;Montreal cognitive assessment;Auditory verbal learning test;Boston naming test;Trail making test;Alzheimer's disease cooperative study-activities of daily living;Transcranial magnetic stimulation-electroencephalogram;Functional Magnetic Resonance Imaging; | — |
Countries
China
Contacts
Public ContactYang Li
the first hospital of hebei medical university
Outcome results
None listed