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Effect of magnesium sulfate on postoperative recovery quality of patients undergoing total laparoscopic hysterectomy under general anesthesia

Effect of magnesium sulfate on postoperative recovery quality of patients undergoing total laparoscopic hysterectomy under general anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500115016
Enrollment
Unknown
Registered
2025-12-21
Start date
2023-08-25
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative recovery quality

Interventions

Experimental group M:In group M, magnesium sulfate injection 40mg/kg was injected intravenously 20min before anesthesia induction.Magnesium sulfate injection (6mg/kg/h) was pumped until the end of the
Control group C:In group C, the same volume of 0.9% normal saline was injected intravenously 20min before anesthesia induction.0.9% normal saline was pumped at the same rate until the end of the opera

Sponsors

The First Affiliated Hospital,University of South China
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. In general anesthesia downlink laparoscopic hysterectomy patients; 2. Age 30-60 years old; 3. The body mass index (BMI) of 18 to 23.9 kg/m^2; 4. American Society of Anesthesiologists (ASA) grade I-II; 5. The operation time was 1h-3h

Exclusion criteria

Exclusion criteria: 1. Because of the language barrier, mental disorders such as unable to cooperate; 2. Patients with heart disease (atrioventricular conduction disorder, hypertension, coronary heart disease); 3. Liver dysfunction (ALT > 40 u/L, AST> 40 u/L); 4. Renal dysfunction (creatinine >177µmol/L); 5. Patients who had taken opioids within 1 months; 6. Patients with a history of nervous system diseases, diabetes mellitus or neuromuscular diseases; 7. Patients with electrolyte disorders; 8. Patients with adrenal insufficiency

Design outcomes

Primary

MeasureTime frame
15-item Quality of Recovery Scale;

Secondary

MeasureTime frame
Recovery, extubation, and retention time in the resuscitation room;The amount of anesthetics used;

Countries

China

Contacts

Public ContactHu Xiaoling

The First Affiliated Hospital,University of South China

781844728@qq.com+86 135 0734 7866

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026