Diagnostic classification in middle-aged women
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Female, aged between 40 and 65 years, right-handed; 2.Education level of >= 6 years; 3.Voluntary participation in the study and provision of signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Bilateral oophorectomy organic lesions of the ovary premature ovarian failure polycystic ovary syndrome and hypothalamic amenorrhea; 2.Those with systemic diseases such as hypertension diabetes coronary heart disease obesity (BMI>=28) etc. and complicated with severe heart liver kidney brain and hematopoietic system diseases; 3.History of mental disorders such as depression bipolar disorder anxiety disorder schizophrenia personality changes etc. and history of alcohol drug or coffee dependence; 4. Pregnant women lactating women and those with a desire to conceive in the next three months; 5.MRI scan contraindications such as the implantation of electronic and metal devices.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neuropsychological cognitive assessment (Self-Rating Anxiety Scale (SAS), Self-Rating Depression Scale (SDS), Montreal Cognitive Assessment (MoCA), Cognitive Failures Questionnaire (CFQ));Multimodal neuroimaging assessment;Menopausal symptom assessment (modified KMI score, MENQOL, Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity Index (ISI), Inventory of Sleep Types (ITQ)); | — |
Secondary
| Measure | Time frame |
|---|---|
| Demographic data (age, sex, body mass index (BMI), education level, etc.); | — |
Countries
China
Contacts
Chengdu University of Traditional Chinese Medicine