Lactation disorder
Conditions
Interventions
Normal group:None
Sponsors
School of Life Science and Technology, Northwestern Polytechnical University
Eligibility
Sex/Gender
All
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Normal Group Participants: (1) Age: 18<=age<=40 years; (2) BMI: 18.5 kg/m^2 <= BMI <= 30.0 kg/m^2; (3) Primiparous women with a singleton vaginal birth or cesarean section; (4) Time window: 3 weeks to 1 year postpartum; (5) Normal lactation, exclusively breastfeeding without the need for supplementary formula; (6) Able to cooperate with data collection before, during, and after lactation; (7) No history of any psychological problems; (8) Able to understand the trial process and provide informed consent independently. 2. Experimental Group Participants: (1) Age: 18<=age<=40 years; (2) BMI: 18.5 kg/m^2 <= BMI <= 30.0 kg/m^2; (3) Primiparous women with a singleton vaginal birth or cesarean section; (4) Time window: 3 days to 1 year postpartum; (5) Able to cooperate with data collection before, during, and after lactation; (6) Able to understand the trial process and provide informed consent independently.
Exclusion criteria
Exclusion criteria: 1. Subjects in the normal group: (1) Multiple pregnancies; (2) History of breast surgery such as breast augmentation or tumor removal; (3) Currently suffering from severe mastitis or breast abscess; (4) Suffering from pituitary tumors, uncontrolled thyroid dysfunction, or other related diseases; (5) History of clearly diagnosed neurological or psychiatric disorders; (6) Scalp infections or damage (affecting EEG-fNIRS electrode placement); (7) Damage or eczema on breast skin (affecting EIM electrode or ultrasound probe placement). 2. Subjects in the experimental group: (1) Multiple pregnancies; (2) History of breast surgery such as breast augmentation or tumor removal; (3) Currently suffering from severe mastitis or breast abscess; (4) Suffering from pituitary tumors, uncontrolled thyroid dysfunction, or other related diseases; (5) History of clearly diagnosed neurological or psychiatric disorders; (6) Scalp infections or damage (affecting EEG-fNIRS electrode placement); (7) Damage or eczema on breast skin (affecting EIM electrode or ultrasound probe placement).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurovascular coupling metrics under simultaneous EEG-fNIRS multimodal acquisition;Neurovascular coupling metrics under simultaneous EEG-fNIRS multimodal acquisition;Milk volume, breastfeeding/pumping, and real-time maternal physiological data; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time-frequency features of EEG during lactation;Hemodynamic characteristics of fNIRS signals during lactation;Neurovascular coupling strength and network topological features based on EEG-fNIRS fusion; | — |
Countries
China
Contacts
Public ContactLi Le
School of Life Science and Technology, Northwestern Polytechnical University
Outcome results
None listed