Skip to content

Effect of total intravenous anesthesia with ciprofol on postoperative recovery quality of patients with thyroid cancer-- A randomized, double-blind, controlled clinical study

Effect of total intravenous anesthesia with ciprofol on postoperative recovery quality of patients with thyroid cancer-- A randomized, double-blind, controlled clinical study

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114971
Enrollment
Unknown
Registered
2025-12-19
Start date
2025-12-22
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

ciprofol group(Group C):Induction: ciprofol 0.4 mg/kg , Maintenance: ciprofol 0.8–2 mg/kg/h, The Ai value was maintained at 40 ~ 60 by adjusting the pumping speed of ciprofol, and the increase or de
Propofol Group (Group P):Induction: Propofol 2 mg/kg , Maintenance: Propofol 5 mg/kg/h, The Ai value was maintained at 40 ~ 60 by adjusting the pump injection rate of propofol, and the increase or dec

Sponsors

Weifang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1 Patients undergoing thyroid cancer surgery; 2 ASA physical status classification I-II; 3 Age 18–65 years; 4 Body mass index (BMI) 18.5–28 kg/m^²

Exclusion criteria

Exclusion criteria: 1 Allergic to research-related drugs; 2 Patients anticipated to have difficult airways; 3 Those on long-term opioid or sedative medication; 4 Pregnant, lactating, or planning pregnancy within the next three months; 5 Cognitive impairment preventing study cooperation

Design outcomes

Primary

MeasureTime frame
QoR-15 questionnaire score on Postoperative Day 1 (POD 1);

Secondary

MeasureTime frame
QoR-15 questionnaire score on postoperative day 3 (POD 3);Use of Vasoactive Drugs;Hemodynamic parameters;Riker Sedation and Agitation Scale (R-SAS) ;Patient Satisfaction Score;time index, Recovery time, recovery room residence time, length of hospital stay after surgery;Consumption of sedative drugs;Whether to use analgesic drugs after operation;Adverse events, such as nausea and vomiting, hypoxemia, hypotension, intraoperative awareness, drowsiness, postoperative delirium, etc.;Injection pain;

Countries

China

Contacts

Public ContactJi Fanceng; Yue Fangli

Weifang People's Hospital

jifanceng@163.com+86 135 6369 8838

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026