Epilepsy
Conditions
Interventions
Gold Standard:Stereotactic Intracranial Electrode Implantation
Index test:Computer-Automated Epileptic Seizure Analysis
Sponsors
Henan Provincial People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with drug-resistant epilepsy; 2. Patients who, after evaluation by scalp video EEG, neuroimaging, neuropsychological assessment, etc., undergo surgical procedures, stereotactic deep electrode implantation, or subdural electrode implantation; 3. Patients without severe intellectual disabilities, able to cooperate and complete experimental tasks; those with a MoCA score below 26 are not to participate in the study; 4. The subject or the subject's guardian agrees to participate and signs the consent form.
Exclusion criteria
Exclusion criteria: 1. There are severe visual or hearing impairments, and due to other organic issues, the person cannot normally understand language; the examiner will ask the patient or their family whether they are willing to participate in this project. A comprehensive assessment will be conducted based on the difficulty of the cognitive experimental tasks and the patient's cognitive ability, developmental status, motor function, emotional state, etc. If the MoCA score is less than 26, the individual will not participate in the study; 2. The control group has severe underlying diseases or other serious neurological disorders besides epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Spatial consistency between pathological high-frequency oscillation regions detected by various algorithms and clinical assessments; | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluation of the resection rate of pathologic high-frequency oscillations detected by various algorithms and the Engel classification of seizure control one year after surgery;Behavioral assessment score of auditory comprehension ability;Speech Communication Ability Behavior Assessment Score;Language Literacy Behavior Assessment Score; | — |
Countries
China
Contacts
Public ContactYazhou Xing
Henan Provincial People's Hospital
Outcome results
None listed