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Application of 18F-FDG PET/CT Multimodal Metabolic Parameters in Invasive Lung Adenocarcinoma: A Diagnostic Test with a Cross-Sectional Study Design

Application of 18F-FDG PET/CT Multimodal Metabolic Parameters in Invasive Lung Adenocarcinoma: A Diagnostic Test with a Cross-Sectional Study Design

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114936
Enrollment
Unknown
Registered
2025-12-19
Start date
2025-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients diagnosed with lung adenocarcinoma

Interventions

Gold Standard:All patients underwent thoracoscopic or open thoracotomy surgery within two weeks of the examination at our hospital to obtain pathological results. Two senior pathologists examined the
Index test:PET multimodal metabolic parameters (SUVmax, SUVmin, SUVmean, SUVpeak, MTV, TLG)

Sponsors

Peking University Shenzhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. The CT image of the lesion shows a single pulmonary lesion with a maximum diameter of <=5 cm; 2. Both lung fields are clearly distinguishable, with no other chest diseases or lymph node abnormalities. 3. The lesion is not adjacent to the liver and the cardiomediastinal blood pool to avoid affecting the delineation of the volume of interest (VOI); 4. High image signal-to-noise ratio and precise fusion registration; 5. Obtain immunohistochemistry (IHC) results; 6. No previous history of tumors.

Exclusion criteria

Exclusion criteria: 1. Patients who cannot obtain pathological results; 2. Patients with poor respiratory cooperation and blurred images; 3. A history of any other malignant tumors within the past 5 years; 4. Known to be allergic to the injection or its excipients; 5. Unable to lie flat or remain still during a PET scan, or intolerant of a PET scan; 6. Those with a history of fractures or anemia in the past year; 7. Patients who do not meet other safety requirements for PET/CT examinations.

Design outcomes

Primary

MeasureTime frame
Sensitivity;Uptake peak;Maximum Standardized Uptake Value;Total amount of glycolysis;Tumor metabolic volume;Mean standardized uptake value;Minimum Standardized Uptake Value;Accuracy rate;specificity;

Secondary

MeasureTime frame
Malignant signs of CT;

Countries

China

Contacts

Public ContactMa Ning

Peking University Shenzhen Hospital

627270963@qq.com+86 755 8392 3333

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026