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Safety Study of Leucine-Restricted Diet in Gastric Cancer Patients

Safety Study of Leucine-Restricted Diet in Gastric Cancer Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114931
Enrollment
Unknown
Registered
2025-12-19
Start date
2025-12-31
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Experimental Group:During the preoperative waiting period after hospital admission, study participants received a leucine-restricted diet for three days prior to surgery. Surgical intervention was per

Sponsors

Qilu Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Pathologically confirmed gastric carcinoma requiring preoperative endoscopic localization marking or delineation of the lesion extent. 2.Aged between 18 and 70 years, regardless of gender. 3.Ability to consume oral or nasogastric tube feeding of a liquid diet. 4.Provision of signed informed consent and voluntary participation in this study. 5.No evidence of distant metastasis on preoperative imaging studies (e.g., CT, PET-CT), and deemed suitable for surgical resection. 6.No concurrent diagnosis of other active malignancies.

Exclusion criteria

Exclusion criteria: 1.Presence of cognitive impairment or psychological disorders that may compromise the understanding of the research content. 2.Diagnosis of Type I or Type II Diabetes Mellitus. 3.Severe diarrhea, intractable vomiting, severe malabsorption syndromes, paralytic or mechanical intestinal obstruction, or active gastrointestinal bleeding. 4.Known allergy to the primary components of the leucine-deficient nutritional formula. 5.Concurrent use of other nutritional supplements that may interfere with the trial's efficacy. 6.Postoperative pathological diagnosis confirming non-primary gastric cancer.

Design outcomes

Primary

MeasureTime frame
Amino acid concentration;

Secondary

MeasureTime frame
CD8+ T cell percentage;

Countries

China

Contacts

Public ContactHui Qu

Qilu Hospital of Shandong University

doctorquhui@email.sdu.edu.cn+86 185 6008 5120

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026