Morbidly obese
Conditions
Interventions
I Group:EIT-based PEEP titration
C Group:Fixed PEEP
Sponsors
The First Affiliated Hospital of Shandong First Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1.American Society of Anesthesiologists ASA Class I to III; 2.18 years old = 65 years old; 3.Laparoscopic gastric volume reduction under elective general anesthesia; 4.35<=BMI<=55 kg/m ² 5.Voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Smoking, previous history of thoracic surgery 2. Received invasive mechanical ventilation within 30 days 3. Pregnancy 4. People allergic to EIT electrode sheets 5. Persistent hemodynamic instability or refractory shock 6. Severe cardiopulmonary diseases (such as severe COPD, NYHA grade III or IV, acute coronary syndrome or persistent ventricular tachycardia) 7. Severe pulmonary hypertension (systolic pulmonary artery pressure > 40mmHg) 8. Increased intracranial pressure, intracranial injury or tumor, or neuromuscular disease 9. Conversion to open surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of pulmonary complications within 72 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Lung ultrasound scores;PACU dwell time;Length of hospitalization;Oxygenation index;Lung drive pressure;Dynamic lung compliance;Pulmonary shunt rate; | — |
Countries
China
Contacts
Public ContactWu Jianbo
The First Affiliated Hospital of Shandong First Medical University (Shandong Qianfoshan Hospital)
Outcome results
None listed