Skip to content

Comparison of clinical effects of bupivacaine liposome used for thoracolumbar fascial space block and incision infiltration anesthesia on postoperative analgesia and recovery quality in patients undergoing lumbar spine surgery

Comparison of clinical effects of bupivacaine liposome used for thoracolumbar fascial space block and incision infiltration anesthesia on postoperative analgesia and recovery quality in patients undergoing lumbar spine surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114914
Enrollment
Unknown
Registered
2025-12-18
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative pain following lumbar surgery

Interventions

Local infiltration group of incision (Group C):Bupivacaine liposomes local infiltration of incision site
Thoracolumbar fascial space block group (R group):Bupivacaine liposome thoracolumbar fascial space block

Sponsors

Fuyang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1.ASA Level I-II; 2.Age range: 18-65 years old; 3.BMI 18-30 kg/m^2; 4.After fully explaining the content of the clinical trial, patients and their families voluntarily joined and signed informed consent.

Exclusion criteria

Exclusion criteria: 1.Preoperative Mini Mental State Examination (MMSE) score <=25 points; 2.History of severe neurological disorders, mental illnesses, and cardiovascular diseases; 3.History of allergy to local anesthetics; 4.Have a history of dependence on painkillers and drug use; 5.Patients with infection at the puncture site and abnormal coagulation function;

Design outcomes

Primary

MeasureTime frame
Total postoperative sufentanil dosage;

Secondary

MeasureTime frame
Stress response and pain mediator indicators;PCIA effective compression frequency, sufentanil, and additional amount of flurbiprofen ester;Cognitive function score;Dosage of propofol and remifentanil used during surgery;Postoperative Recovery Quality Score;VAS pain scores during rest and turning over;Time of first use of analgesics after surgery;Adverse reaction occurrence;Incidence of chronic pain;

Countries

China

Contacts

Public ContactWu Meichao

Fuyang People's Hospital

ksly0501@163.com+86 181 1053 1585

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026