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A Systemic Panoramic Analysis of Osteoarthritis Joint Tissues

Multi-omics Characterization of Articular Tissues in Osteoarthritis Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114910
Enrollment
Unknown
Registered
2025-12-18
Start date
2025-12-25
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Osteoarthritis group:None
Non-osteoarthritis (control group):None

Sponsors

Ningbo First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18–85 years; 2.imaging and clinically confirmed osteoarthritis; 3.scheduled for elective joint surgery with anticipated availability of discardable bone tissue; 4.provision of voluntary written informed consent. (Total target enrollment: 80 cases).

Exclusion criteria

Exclusion criteria: 1.Active autoimmune or connective tissue diseases; 2.severe coagulation dysfunction or other conditions unsuitable for study participation; 3.any other circumstances deemed by the investigator as inappropriate for enrollment.

Design outcomes

Primary

MeasureTime frame
Molecular characteristics of bone tissue based on single-cell/single-nucleus transcriptomics;—

Secondary

MeasureTime frame
Clinical relevance;—

Countries

China

Contacts

Public ContactZhu YingChun

Ningbo First Hospital

zyc198201@163.com+86 574 8708 5111

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026