Patients with locally advanced or metastatic NSCLC
Conditions
Interventions
NSCLC group:None
Sponsors
Nanjing Drum Tower Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age over 18 years; 2. Patients with locally advanced or metastatic non-small cell lung cancer confirmed by histology or cytology to be negative for driver gene mutations (negative for EGFR mutations and negative for ALK rearrangements); 3. Measurable lesions according to the Response Evaluation Criteria in Solid Tumors (RECIST); 4. ECOG performance status of 0-2.
Exclusion criteria
Exclusion criteria: 1. patients who cannot be followed up; 2. patients who discontinued ICI treatment for reasons other than disease progression or death; 3. patients who have previously received ICI treatment; 4. expected survival time less than 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-free survival (PFS) at 1-year follow-up; | — |
Secondary
| Measure | Time frame |
|---|---|
| 6-month Objective Response Rate (ORR);1-year overall survival (OS);2-year PFS and OS; | — |
Countries
China
Contacts
Public ContactChen Yuxin
Nanjing Drum Tower Hospital
Outcome results
None listed