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Clinical study on half of the effective dose of remifentanil used for gastroscopy under deep sedation in elderly patients

Clinical study on half of the effective dose of remifentanil used for gastroscopy under deep sedation in elderly patients

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114882
Enrollment
Unknown
Registered
2025-12-18
Start date
2025-09-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None

Interventions

Refentanil group:Refentanil

Sponsors

The Affiliated Hospital of Xuzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age 60-80 years old, gender-limited; 2. ASA classification grade I-III; 3. BMI 18-28 kg/m2; 4. Painless gastroscopy; 5. Gastroscopy operation time is expected to not exceed 20 minutes; 6. I can voluntarily cooperate with this study;

Exclusion criteria

Exclusion criteria: 1. Severe respiratory, cardiovascular system diseases and liver and kidney dysfunction and coagulation insufficiency; 2. People who are known to be allergic to or have contraindications to opioids and their rescue drugs, benzodiazepines and their rescue drugs; 3. Those suffering from mental system diseases (schizophrenia, mania, insanity, etc.) and those with a history of long-term use of psychotropic drugs and cognitive dysfunction; 4.Have a history of drug abuse, drug abuse and alcoholism. Alcoholism means daily average drinking >2 units of alcohol (1 unit = 360mL beer or 45mL liquor with an alcohol content of 40% or 150mL wine); 5. The researcher or operating physician believes that patients are not suitable to participate in this trial; 6. Refusal to sign the informed consent form;

Design outcomes

Primary

MeasureTime frame
The incidence of body movement reactions during gastroscopy;

Secondary

MeasureTime frame
Leave the hospital;Hemodynamics;The patient's satisfaction;The duration of revival;Discomfort reaction rate;The duration of gastroscopy;SpO2 <94% incidence and duration;The endoscopist's satisfaction;SpO2 <90% incidence and duration;Adverse reaction rate;The score of modified obsevers assessment of alertness/sedation scale (MOAA/S) after induction;

Countries

China

Contacts

Public ContactMengxing Jia

The Affiliated Hospital of Xuzhou Medical University

jmx5278@163.com+86 516 85802297

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026