Mechanism Research on Genetic Mutation-Related Familial Neuromyelitis Optica

Mechanism Research on COPA Genetic Mutation-Related Familial Neuromyelitis Optica

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500114868

Enrollment

Unknown

Registered

2025-12-18

Start date

2025-12-23

Completion date

Unknown

Last updated

2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

NMOSD

Interventions

Group of patients with familial neuromyelitis optica:None

Non-familial neuromyelitis optica patient cohort:None

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria of the 2025 Guidelines for Neuromyelitis Spectrum Diseases; 2. Age >=18 years old; 3. Sign informed consent form;

Exclusion criteria

Exclusion criteria: 1. Severe infectious diseases; 2. Immunosuppressant therapy has been initiated;

Design outcomes

Primary

Measure	Time frame
C gene mutation status;	—

Secondary

Measure	Time frame
Serum IFN-ß;Serum IFN-a;IL-6;	—

Countries

China

Contacts

Public ContactLi Miaodan

Southern Medical University Southern Hospital

limiaodan90@163.com+86 10 1234 5678

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026