Osteoarthritis and end-stage knee disease
Conditions
Interventions
Low-dose group:After undergoing total knee arthroplasty (TKA), the patient was transferred to the anesthesia recovery room for observation. Under ultrasound guidance, combined with a nerve stimulator,
Medium-dose group:After undergoing total knee arthroplasty (TKA), the patient was transferred to the anesthesia recovery room for observation. Under ultrasound guidance, combined with a nerve stimulat
Sponsors
Foshan Fosun Chancheng Hospital
Eligibility
Sex/Gender
All
Age
55 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age: 55 to 80 years old; 2. ASA classification is grade II or III; 3. 18 kg/m^2 or less a BMI of 30 kg/m^2 or less; 4. Unilateral total knee arthroplasty (TKA) under elective combined spinal-epidural anesthesia; 5. The subjects voluntarily participated in this trial and signed the informed Consent Form (ICF).
Exclusion criteria
Exclusion criteria: 1. History of common peroneal nerve injury or neuromuscular diseases; 2. History of severe cardiovascular or cerebrovascular diseases, hepatic or renal dysfunction, cerebral stroke, or peptic ulcer disease. 3. Allergy to local anesthetics or opioids. 4. Communication disability, or history of psychological or psychiatric disorders. 5. Contraindications to regional nerve block (e.g., coagulopathy, local infection at the injection site). 6. History of alcohol abuse, or use opioid or sedative medications preoperatively; 7.The subjects refused to be included in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ankle flexion and extension range of motion;Strength of the dorsiflexor muscles of the ankle; | — |
Secondary
| Measure | Time frame |
|---|---|
| Resting Visual Analogue Scale (RVAS) score and motor Visual Analogue Scale (MVAS) score;Score of numbness degree in the area innervated by the sciatic nerve; | — |
Countries
China
Contacts
Public ContactJiaming Dai
Foshan Fosun Chancheng Hospital
Outcome results
None listed