Depressive disorder
Conditions
Interventions
Intervention group:The Intervention Group receives a 4-week VR-based combined intervention on the basis of conventional drug treatment administered to the Control Group. Basic treatment is centered on
the intervention is core to VR scenario-based interactive training, where patients are required to respond to task requirements to advance the narrative. The main forms include a progressive increase
Control group:Centered on conventional therapy with SSRIs, the dosage is adjusted to a reasonable range according to the severity of illness, with a treatment course of 4 weeks.
Sponsors
Xinxiang Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients aged 10 to 19 years; 2. Diagnosed with depressive disorders by psychiatrists in accordance with the diagnostic criteria specified in the International Classification of Diseases, 10th Revision (ICD-10); 3. Undergoing stable pharmacotherapy; 4. With normal reading and writing abilities and no communication disorders; 5. Patients and their family members have provided informed consent and voluntarily participate in this study.
Exclusion criteria
Exclusion criteria: 1. With comorbid or past history of organic brain disorders, severe traumatic brain injury, or personal/family history of epilepsy; 2. Patients with severe abnormalities of cardiac, hepatic, or renal function; 3. Patients with severe physical illness; or those with a history of substance dependence or abuse (e.g., alcohol, cocaine, or other substances); 4. With comorbid other mental illnesses, such as schizophrenia, hypomanic or manic episodes of bipolar disorder, or others; 5. With a history of motion sickness and vertigo, or presence of any active nausea or vomiting.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton Depression Scale Score;Children’s Depression Inventory Score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hamilton Anxiety Scale Score;Montreal Cognitive Assessment Score;Heart Rate Variability; | — |
Countries
China
Contacts
Public ContactJunqiang Zhao
Xinxiang Medical University
Outcome results
None listed