Impacted tooth
Conditions
Interventions
Alfentanil group:none
Sponsors
School and Hospital of Stomatology, Hebei Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: (1) Age ranged from 18 to 65 years; (2) American Society of Anesthesiologists (ASA) physical status classification of Grade I-II ; (3) Expected operation duration between 30 minutes and 2 hours; (4) Anesthesia protocol was total intravenous anesthesia (TIVA) or combined intravenous-inhalation anesthesia, with alfentanil or sufentanil as the main intraoperative analgesic.
Exclusion criteria
Exclusion criteria: (1) Severe hepatic or renal insufficiency (Child-Pugh Class C or estimated glomerular filtration rate [eGFR] 200ml or requirement for blood transfusion; (4) Allergy to any drugs involved in this study; (5) Intraoperative use of other adjuvant analgesics (e.g., ketamine, dexmedetomidine); (6) Severe deficiency of medical record data (e.g., lack of continuous intraoperative vital sign records or key medication records); (7) Known difficult airway or significant changes in intraoperative anesthesia protocol; (8)Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| hemodynamic stability; | — |
Secondary
| Measure | Time frame |
|---|---|
| Baseline data: demographic information (age, gender, weight, height, body mass index [BMI]), ASA classification, comorbidities (e.g., hypertension, diabetes),and preoperative baseline vital signs (the average of three consecutive measurements of MAP and HR in a calm state after entering the operating room);Perioperative data:type and duration of surgery,duration of anesthesia,types and doses of all medications administered ;Awakening time;Time to achieve a Steward score 6;PACU length of stay;Incidence of intraoperative hypertensionand intraoperative hypotension;Incidence of adverse events(e.g.,respiratory depression,nausea and vomiting,dizziness)in the PACU and the dosage of rescueanalgesics administered; | — |
Countries
China
Contacts
Public ContactHe Zexiu
School and Hospital of Stomatology, Hebei Medical University
Outcome results
None listed