Dentition defect
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 50 years and older. 2. In need of delayed implant placement in a single tooth gap at posterior healing sites. 3. Conducted routine annual physical examinations or specialized endocrine assessments which involved DXA measurement of BMD at the spine, hip, or forearm with a T-score above -2.5 within one year prior to oral implant therapy. 4. Presence of intra-osseous buccal bone dehiscence with a defect width of 1-3 mm and a defect depth of less than 50% of the implant length after implant placement. 5. Participants who have signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Diagnosis of osteoporosis based on DXA measurement of BMD at the spine, hip, or forearm (a T-score at -2.5 or more below) within the past 12 months 2. History of treatment with antiresorptive agents like bisphosphonates and denosumab). 3. Affected by other systemic diseases related to bone metabolism (e.g., Cushing's syndrome, Addison'sdisease and rheumatoid arthritis). 4. Psychological or psychiatric disorders requiring medication and unable to receive oral implant therapy. 5. Presenting an acute endodontic/periodontal lesion in the neighbouring areas to the implant site. 6. History of chemotherapy within 5 years prior to oral implant therapy. 7. History of radiation in the head and neck region. 8. Present alcohol and/or drug abuse. 9. History of smoking (>10 cigarettes per day). 10. Bone grafting extends more than 1 mm beyond the contour of the alveolar bone on CT cross-sections.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Alveolar ridge width change; | — |
Secondary
| Measure | Time frame |
|---|---|
| Patient reported outcomes (VAS pain score);Postoperative complications;Marginal bone loss;Implant tissue health status;Implant survival rate; | — |
Countries
China
Contacts
West China Hospital of Stomatology, Sichuan University