Ossification of the posterior longitudinal ligament of the cervical spine
Conditions
Interventions
The immature ossification group:None
Mature ossification group:None
The non-ectopic ossification group:None
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.Aged between 35 and 70 years old, gender not restricted, and voluntarily signing the informed consent form. 2.The diagnosis was confirmed as cervical posterior longitudinal ligament ossification (the patient presented with clinical symptoms of spinal cord or nerve root damage, such as dysfunction and sensory impairment in limbs and trunk, bladder and rectum dysfunction, and pathological reflexes in limbs; X-ray or CT confirmed the presence of ectopic ossification in the posterior longitudinal ligament). The diagnosis was also confirmed as cervical spondylosis (the patient presented with clinical symptoms of spinal cord or nerve root damage, such as dysfunction and sensory impairment in limbs and trunk, bladder and rectum dysfunction, and pathological reflexes in limbs; X-ray or CT could not clearly show the presence of ectopic ossification in the posterior longitudinal ligament, and MRI showed that the spinal cord compression was of low signal intensity). 3.The symptoms and signs progressively worsened and conservative treatment was ineffective.
Exclusion criteria
Exclusion criteria: 1.Patients who have participated in other clinical trials within the past three months. 2.Congenital malformations (including but not limited to occipitocervical malformations, congenital cervical fusion, and cervical-related neurovascular malformations), cervical trauma, cervical tumors, and inflammatory diseases such as cervical tuberculosis. 3.Those with motor neuron diseases such as amyotrophic lateral sclerosis and other neurological disorders. 4.The patient's condition is poor and they cannot withstand the surgery, or the patient is not suitable for surgical treatment as determined by preoperative examinations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Accuracy rate;Precision rate;Recall rate; | — |
Countries
China
Contacts
Public ContactKong Qingjie
Shanghai General Hospital
Outcome results
None listed