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A clinical study on the safety and efficacy of anesthesia with target-controlled infusion of remimazolam or propofol in endobronchial ultrasound diagnosis and treatment

A clinical study on the safety and efficacy of anesthesia with target-controlled infusion of remimazolam or propofol in endobronchial ultrasound diagnosis and treatment

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114815
Enrollment
Unknown
Registered
2025-12-17
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lesions of the lungs, trachea, and mediastinum

Interventions

Experimental group:Remimazolam + Alfentanil
Control group:Propofol + Alfentanil

Sponsors

Affiliated Hospital of Jiangsu University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1.Patients undergoing elective endobronchial ultrasound examination; 2.American Society of Anesthesiologists (ASA) physical status classification ?-?; 3.Age 18-60 years; 4.Body Mass Index (BMI) 18-25 kg/m²; 5.Voluntarily participate in the study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Complicated with hypoxemia; 2.Inadequately controlled potentially life-threatening cardiovascular and respiratory diseases; 3.Diabetes mellitus or hepatic/renal insufficiency; 4.Severe hemostatic dysfunction; 5.Anemia; 6.Allergy to sedative/anesthetic drugs; 7.Complicated with neurological or psychiatric disorders, or those taking psychotropic drugs.

Design outcomes

Primary

MeasureTime frame
Quality of Recovery-15;Incidence of Intraoperative Respiratory Depression;

Secondary

MeasureTime frame
Severity of coughing during the induction period;Induction endpoint time;Incidence of coughing response during induction;Time of regaining consciousness;Ramsay Sedation Scale Score;Postoperative Nausea and Vomiting(PONV) Score;The satisfaction of anesthesiologists and endobronchial ultrasound operators with the anesthetic effect;Other postoperative adverse reactions;Blood pressure(BP);Heart rate(HR);Pulse oxygen saturation(SpO?);

Countries

China

Contacts

Public ContactJiang Peng

Affiliated Hospital of Jiangsu University

doctorjp@163.com+86 139 1455 6527

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026