Gallbladder dysfunction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: The critically ill patients receiving mechanical ventilation admitted to ICU of Emergency Department of Cangzhou Central Hospital: 1. Age>=18 years old; 2. Acute Physiology and Chronic Health Evaluation-?(APACHE-?) scores > 8 points.
Exclusion criteria
Exclusion criteria: Age <18 years old; length of hospitalization < 24h; pregnany; patients with previous history of gallstones, bile duct stones, intrahepatic and intrahepatic bile duct diseases, cirrhosis; patients with acute cholecystitis, cholangitis, or mechanical intestinal obstruction; patients who could not receive enteral nutrition within 7 days due to gastrointestinal surgery or other reasons; patients who could not receive ultrasonic examination due to abdominal distension or other reasons; and patients with advanced cancer, end-stage multiple organ failure or without informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ultrasonography of gallbladder;liver function test;Duration of gallbladder dysfunction and incidence of acute cholecystitis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Highest grade and duration of acute gastrointestinal injury;cholecystokinin;Intra-abdominal pressure;Application of Enteral and Parenteral Nutrition;Duration of mechanical ventilation, length of ICU stay, length of hospital stay, and survival/mortality.; | — |
Countries
China
Contacts
Cangzhou Central Hospital