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A Prospective, Randomized, Controlled Trial of a Dual-Track Intervention Based on the Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) to Improve Ultrasound Diagnostic Performance for Thyroid Nodules

A Prospective, Randomized, Controlled Trial of a Dual-Track Intervention Based on the Chinese Thyroid Imaging Reporting and Data System (C-TIRADS) to Improve Ultrasound Diagnostic Performance for Thyroid Nodules

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114784
Enrollment
Unknown
Registered
2025-12-17
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroid Nodules

Interventions

intervention group:dual-track intervention

Sponsors

Ankang Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Age 18–75 years; 2. Thyroid nodules detected by color Doppler ultrasound and classified with TI-RADS; 3. Either solitary or multiple nodules are acceptable, but the largest suspicious nodule must be >=0.4 cm in diameter and exhibit at least one high-risk ultrasound feature; 4. Willing and able to undergo routine examinations, comply with the "dual-track intervention" protocol, and complete 12 months of follow-up; 5. Written informed consent obtained.

Exclusion criteria

Exclusion criteria: 1. History of neck surgery or radiotherapy that has led to significant anatomical alteration; 2. Pregnant or lactating women; 3. Contraindications to probe contact, such as open wounds or infections; 4. Ultrasound images with uncorrectable, significant quality defects; 5. Presence of other active malignant tumors.

Design outcomes

Primary

MeasureTime frame
Magnitude of improvement in the completeness rate of key-plane acquisition.;Diagnostic accuracy;magnitude of reduction in probe overspeed event incidence;Diagnostic Methods;

Secondary

MeasureTime frame
Alterations in Blood Flow Grade Distribution;

Countries

China

Contacts

Public ContactHengtao Song

Ankang Hospital of Traditional Chinese Medicine

2103847089@qq.com+86 915 818 3624

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026