Patients undergoing general anesthesia with sufentanil-induced tracheal intubation
Conditions
Interventions
Group T (Tiglyldine Group):1 mg of tigelidine is prepared in 5 ml of solution
Group S (Normal Saline Control Group):5 ml of 0.9% normal saline
Sponsors
Yan‘an Hospital of Kunming City
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.ASA class I-III 2.Aged 18-70 years 3.Require the use of sufentanil for endotracheal intubation under general anesthesia induction 4.Voluntarily signed informed consent form
Exclusion criteria
Exclusion criteria: 1.Allergy 2.Sinus bradycardia 3.Severe neurological, respiratory, or cardiovascular diseases 4.History of anesthetic drug dependence and recent opioid use 5.History of smoking 6.Hepatic or renal dysfunction 7.Gallbladder surgery 8.Pregnancy, lactation, and surgery for childbirth 9.Patients with conditions that may lead to spontaneous coughing, such as upper respiratory tract infection within the past 2 weeks
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence of cough following sufentanil injection; | — |
Secondary
| Measure | Time frame |
|---|---|
| Number of patients with coughs of different severity grades;Systolic blood pressure;Diastolic blood pressure;Heart rate;Pulse oxygen saturation ;Other side effects associated with tiglyldine and sufentanil; | — |
Countries
China
Contacts
Public ContactLi Bingxing
Yan‘an Hospital of Kunming City
Outcome results
None listed