Acute Ischemic Stroke
Conditions
Interventions
Control Group:Upon admission, all patients with acute cerebral infarction shall receive standardised pharmacological treatment comprising oral aspirin, oral atorvastatin 20mg, intravenous infusion of
Intervention Group:Upon admission, all patients with acute cerebral infarction received standardised pharmacological treatment comprising oral aspirin, oral atorvastatin 20mg, intravenous Shuxuetong i
Sponsors
The Fourth Affiliated Clinical Hospital of Changchun University of Traditional Chinese Medicine (Changchun People's Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1.All patients met the diagnostic criteria for stroke revised at the 4th National Cerebrovascular Disease Conference of the Chinese Medical Association in 1995 and were confirmed by cranial CT or MRI; 2.First-time onset, age < 70 years. 3.Patients were in a relatively stable condition, conscious, provided personal consent, and were able to actively cooperate with the examination. 4.All patients had unilateral limb dysfunction (hemiplegia), within 48 hours of onset, presenting with a single episode of unilateral cortical/subcortical infarction (confirmed by imaging), an NIHSS score of 6-20, and a Fugl-Meyer Assessment score for the hemiplegic limb < 50 (indicating moderate to severe motor impairment).
Exclusion criteria
Exclusion criteria: 1. Hearing comprehension and cognitive impairments; 2. Peripheral neuropathy caused by drug-induced damage, chemical injury, radiation damage, heavy metal poisoning, diabetes, chronic alcohol consumption, or severe peripheral vascular disease; 3. Spinal cord or radicular cervical spondylosis; severe lumbar disc herniation affecting the spinal cord; 4. Mononeuropathy (e.g., carpal tunnel syndrome); 5. Joint subluxation; 6. Localised nerve injury resulting from limb deformity or trauma; 7. Severe cardiac, hepatic, or renal insufficiency; 8. Patient or family refusal to consent to enrolment; 9. Patients unable to attend follow-up appointments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Electromyographic (EMG) Action Potential and Nerve Conduction Velocity (NCV); | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood light chain protein; | — |
Countries
China
Contacts
Public ContactYunhao Ge
The Fourth Affiliated Clinical Hospital of Changchun University of Traditional Chinese Medicine (Changchun People's Hospital)
Outcome results
None listed