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Regulatory Mechanisms of Phase Separation in Gelatin-Oligosaccharide-Polyphenol Blends on Gel Formation, Polyphenol Stability and Astringency

Regulatory Mechanisms of Phase Separation in Gelatin-Oligosaccharide-Polyphenol Blends on Gel Formation, Polyphenol Stability and Astringency

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114768
Enrollment
Unknown
Registered
2025-12-17
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Not involved

Interventions

test group:None

Sponsors

Nankai University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1.Aged 18-45 years, regardless of gender (n=50). 2.In good general health with no oral diseases. 3.Has not recently taken any medication known to affect saliva secretion. 4.Willing to participate in the study and provide written informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with significant systemic diseases, such as diabetes, hypertension, cardiovascular diseases, hematological disorders, rheumatoid arthritis, malignant tumors, asthma, inflammatory bowel disease, Crohn's disease, psoriasis, etc. 2.Individuals with poor oral hygiene or moderate to severe periodontitis. 3.Patients with other severe oral mucosal diseases. 4.Use of immunomodulatory drugs within the past 3 months, antibiotics within the past month, or local medicinal treatment of the lesions within the past week. 5.Patients with significant salivary gland disorders, such as Sjögren's syndrome or salivary gland tumors. 6.Inability to cooperate with the saliva collection procedure.

Design outcomes

Primary

MeasureTime frame
Salivary protein composition;Salivary lubricity;Salivary protein precipitation volume;

Countries

China

Contacts

Public ContactRuican Wang

Nankai University

rcwang@nankai.edu.cn+86 22 8535 8144

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026