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Effect of Oliceridine on Quality of Recovery for Patient-Controlled Intravenous Analgesia after Thoracic Surgery: A Randomized Double-Blind Trial

ERAS-Driven Use of the G Protein-Biased µ-Opioid Receptor Agonist Oliceridine for Analgesia After VATS Pulmonary Surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114767
Enrollment
Unknown
Registered
2025-12-17
Start date
2026-01-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enhanced Recovery After Surgery after Thoracic Surgery

Interventions

Sponsors

Enze Hospital, Taizhou Enze Medical Center (Group)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 64 Years

Inclusion criteria

Inclusion criteria: 1.All patients scheduled to undergo video-assisted thoracic surgery for pulmonary resection;

Exclusion criteria

Exclusion criteria: 1.American Society of Anesthesiologists (ASA) physical status III or higher; 2.Age >=65 years or =30 kg/m² or < 18 kg/m²; 4.Pre-existing hepatic or renal dysfunction; 5.History of upper respiratory tract infection within the past week; 6.History of alcohol abuse; 7.Long-term use of sedative or analgesic medications; 8.Visual or auditory impairment severe enough to hinder normal communication; 9.Coexisting psychiatric disorders; 10.Pregnancy or lactation; 11.Patient refusal;

Design outcomes

Primary

MeasureTime frame
QoR-15 score at 24 hours after surgery;QoR-15 score at 48 hours after surgery;

Secondary

MeasureTime frame
First time out of bed after surgery;Discharge time;Incidence of pulmonary complications;Comparison of individual item of QoR-15 scores between groups at 24 and 48 hours;

Countries

China

Contacts

Public ContactRui Lu

Enze Hospital, Taizhou Enze Medical Center (Group)

lur0805@enzemed.com+86 182 6801 7945

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026