Comparison of remimazolam and ciprofol on postoperative delirium in elderly patients undergoing general anesthesia: a prospective, randomized, controlled clinical trial

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500114762

Enrollment

Unknown

Registered

2025-12-17

Start date

2026-01-01

Completion date

Unknown

Last updated

2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Delirium

Interventions

Remimazolam Group:remimazolam for induction and maintenance of anesthesia

Ciprofol Group:ciprofol for induction and maintenance of anesthesia

Eligibility

Sex/Gender

All

Age

60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. ASA II–III classification 2. Aged 60–80 years 3. Elderly patients undergoing general anaesthesia.

Exclusion criteria

Exclusion criteria: 1. BMI > 28 kg/m² or BMI < 18.5 kg/m²; 2. Pre-operative cognitive impairment or abnormal mental status; 3. Presence of severe cerebrovascular disease or related sequelae; 4. History of post-operative delirium; 5. History of long-term sedative medication use; 6. History of chronic alcohol consumption; 7. Known allergy to anaesthetic agents.

Design outcomes

Primary

Measure	Time frame
incidence of postoperative delirium;	—

Secondary

Measure	Time frame
mean arterial pressure;heart rate;recovery time;	—

Countries

China

Contacts

Public ContactHu Yuping

The Fourth Affiliated Hospital of Nanjing Medical University

yupinghu163@163.com+86 138 0903 7917

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026