Comparison of Pain Management Medications for Emergency Patients on Ventilators

Observational Clinical Study Comparing Remifentanil versus Butorphanol in Emergency Department Patients on Mechanical Ventilation

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2500114758

Enrollment

Unknown

Registered

2025-12-17

Start date

2026-01-01

Completion date

Unknown

Last updated

2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute pain in emergency patients requiring mechanical ventilation

Interventions

Remifentanil group:Remifentanil hydrochloride for injection

Butorphanol:Butorphanol tartrate injection

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >=18 years, any gender; 2.Emergency patients on mechanical ventilation requiring analgesic therapy with expected ventilation duration >=24h; 3.Informed consent obtained from patient or family;

Exclusion criteria

Exclusion criteria: 1.Pregnant or lactating women; 2.Known allergy to study drugs; 3.Use of analgesics other than remifentanil or butorphanol within the past week; 4.History of long-term opioid use or addiction; 5.Intestinal obstruction at risk; 6.Previous or concurrent participation in other studies;

Design outcomes

Primary

Measure	Time frame
Rescue sedation rate;CPOT pain score;	—

Secondary

Measure	Time frame
Duration of mechanical ventilation;	—

Countries

China

Contacts

Public ContactChen Yuanzhuo

Shanghai Tenth People's Hospital

chenyuanzhuo@tongji.edu.cn+86 189 1768 4098

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026