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The influence of different combinations of lower extremity nerve blocks on postoperative analgesia and rehabilitation quality after total knee arthroplasty: A prospective, randomized controlled study

The influence of different combinations of lower extremity nerve blocks on postoperative analgesia and rehabilitation quality after total knee arthroplasty: A prospective, randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114747
Enrollment
Unknown
Registered
2025-12-17
Start date
2025-12-29
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative analgesia and rehabilitation quality of total knee arthroplasty

Interventions

ACB+iPACK Group:Preoperative ultrasound-guided adductor canal block combined with iPACK block
ACB+PPB Group:Preoperative ultrasound-guided adductor canal block combined with PPB block
FTB+iPACK Group:Preoperative ultrasound-guided femoral triangle block combined with iPACK block
FTB+PPB Group:Preoperative ultrasound-guided femoral triangle block combined with PPB block
Intra-articular injection of local anesthetic Group:Intra-articular injection of local anesthetic on the surgical side

Sponsors

The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients aged 50 to 80 years old, of either gender; with a BMI of 18 to 35 kg/m^²; with an ASA score of I to III; with complete clinical data; who are scheduled to undergo their first unilateral total knee arthroplasty; and who clearly understand, voluntarily participate in this study and sign the informed consent form.

Exclusion criteria

Exclusion criteria: Those with a history of knee joint surgery; those with severe systemic organ dysfunction; those with a history of allergy to anesthetics; those with skin damage, dermatitis or infection at the puncture site; those who have been using analgesics for a long time; those with mental disorders or cognitive dysfunction; those currently participating in other clinical studies.

Design outcomes

Primary

MeasureTime frame
VAS score at rest;VAS score at movement;PACU stay time;The first time to get out of bed;Inhospital time;Total dosage of sufentanil;Degree of active motion of the knee joint;Quadriceps muscle strength;

Secondary

MeasureTime frame
Mean arterial pressure;Heart rate;Operation time;Extubation time;Adverse reaction ;

Countries

China

Contacts

Public ContactLing Guo

The First Affiliated Hospital of Wannan Medical College, Yijishan Hospital

guolingshirley@163.com+86 135 1491 2660

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026