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Assessment of Cytotoxicity, Genotoxicity in Exfoliated Buccal Mucosa Cells following OPG and CBCT

The ResearchOf Cytotoxicity, Genotoxicity And Oxidative Stress Response On Exfoliated Buccal Mucosa Cells Upon OPG And CBCTRadiations Exposure Across Two Different Age Groups

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114733
Enrollment
Unknown
Registered
2025-12-17
Start date
2024-11-12
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

The genotoxicity of x ray

Interventions

Sponsors

Universiti Sains Malaysia
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Individuals with no harmful habits such as smoking, alcohol consumption and/or betel nut chewing. 2. Individuals who have not been exposed to X-rays in the past three months and will undergo dental X-ray examination within one hour. 3. No oral mucosal diseases. 4. No local irritating factors.

Exclusion criteria

Exclusion criteria: Patients who do not meet all of the above inclusion criteria and exhibit any of the following characteristics will be excluded: 1. Systemic diseases such as leukemia, lymphoma, rheumatic diseases, diabetes, etc. 2. History of treatments such as head and neck radiation therapy, immunosuppressive, or cytotoxic drugs. 3. Individuals with infectious diseases or inflammatory conditions. 4. Local pathological changes, such as macroscopic abnormalities, gum and periodontal diseases. 5. Pregnant women. 6. Individuals wearing removable dentures or intra-oral appliance.

Design outcomes

Primary

MeasureTime frame
Genotoxicity;

Countries

Malaysia

Contacts

Public ContactYaxin Wang

Universiti Sains Malaysia

wangyaxin@student.usm.my+86 181 3596 6357

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026