Diagnosed as acute decompensated heart failure
Conditions
Interventions
Standard Therapy Group:NA
Standard Therapy + rhBNP Group:NA
Sponsors
Xuanwu Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age 18 years or above, and gender not limited. 2. Clinically diagnosed as ADHF (NYHA cardiac function classification: grade III-IV); 3. Expected hospitalization duration >= 72 hours; 4. Systolic blood pressure >= 100 mmHg; 5. Sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to any component of recombinant human brain natriuretic peptide; 2. Patients who were using ARNI before admission (and had been using it continuously prior to hospitalization); 3. Patients with untreated tumors; 4. Pregnant women, lactating women, or those planning to become pregnant within the next 3 months; 5. Patients with severe renal insufficiency requiring dialysis; 6. Patients with major organ dysfunction or failure; 7. Within 30 days prior to signing the informed consent form, one has participated in other clinical studies and received trial interventions (such as trial drugs or medical devices), or is still within the visit period of another clinical study. 8. The researchers believe that any other situation that might pose risks to the patients;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in NT-proBNP level; | — |
Secondary
| Measure | Time frame |
|---|---|
| 30-day readmission rate for heart failure; | — |
Countries
China
Contacts
Public ContactZhi Liu
Xuanwu Hospital, Capital Medical University
Outcome results
None listed