analgesic effect of erector spinae plane block and wound infiltration on postoperative pain following lumbar fusion surgery

the analgesic effect of erector spinae plane block and wound infiltration on postoperative pain following lumbar fusion surgery: a multi-center randomized study

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500114714

Enrollment

Unknown

Registered

2025-12-17

Start date

2026-01-01

Completion date

Unknown

Last updated

2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lumbar spinal stenosis, lumbar spondylolisthesis

Interventions

WI group:local infiltration of wound

ESPB group:ultrasound guided erector spinae plane block

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.age from 18 to 80 years old; 2.american society of anesthesiologists physical status: grade I to III; 3.Weight >=50kg; 4.BMI 19-30kg.m^2;

Exclusion criteria

Exclusion criteria: 1.chronic opioid dependence or use of NSAIDs for more than 3 months. 2.patients who underwent corrective surgery for degenerative scoliosis or kyphosis, or revision surgery; 3.BMI >40 kg/m²; 4.allergy to bupivacaine or liposomal bupivacaine; 5.severe neurological or cognitive disease; 6.contraindications of regional anesthsia; 7.severe renal (serum creatinine > 442 µmol/L or requiring renal replacement therapy) or liver (Child–Pugh grade C) insufficiency,; 8.pregnancy; 9.patient's refusal; 10.admission to ICU postoperatively;

Design outcomes

Primary

Measure	Time frame
Physical Activity VAS Score;cumulative opioid consumption 72h postoperatively;	—

Secondary

Measure	Time frame
Resting VAS score;VAS score at movement 48 hours postoperatively;VAS score at rest 72 hours postoperatively;VAS score at movement 72 hours postoperatively;cumulative opioid consumption 48h postoperatively;VAS score at rest 24 hours postoperatively;the time of first rescue analgesia;postoperative complications;quality of recovery 72h postoperative;postoperative length of hospital stay;postoperative adverse events;cumulative opioid consumption 24h postoperatively;	—

Measure

Time frame

Resting VAS score;VAS score at movement 48 hours postoperatively;VAS score at rest 72 hours postoperatively;VAS score at movement 72 hours postoperatively;cumulative opioid consumption 48h postoperatively;VAS score at rest 24 hours postoperatively;the time of first rescue analgesia;postoperative complications;quality of recovery 72h postoperative;postoperative length of hospital stay;postoperative adverse events;cumulative opioid consumption 24h postoperatively;

—

Countries

China

Contacts

Public ContactMa Lulu

Peking Union Medical College Hospital

malulu@pumch.cn+86 10 69152020

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026