Hypertrophic Obstructive Cardiomyopathy
Conditions
Sponsors
General Hospital of Northern Theater Command
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)Diagnosed with drug-refractory hypertrophic obstructive cardiomyopathy. 2)Scheduled to undergo the modified Morrow procedure. 3)Availability of pre-operative cardiac ultrasound (echocardiography) images. 4)Age >= 14 and <= 80 years.
Exclusion criteria
Exclusion criteria: 1)Presence of any surgical contraindications (e.g., uncontrolled infection, irreversible severe pulmonary hypertension, etc.). 2)Pre-operative left ventricular ejection fraction (LVEF) < 0.3. 3)Previous history of Morrow procedure. 4)Poor-quality pre-operative echocardiographic images that preclude accurate assessment of the left ventricular outflow tract pressure gradient. 5)Concurrent acute myocardial infarction with onset within less than 7 days. 6)Comorbid with severe hepatic, renal, or pulmonary failure, or any other disease with a life expectancy of < 1 year. 7)Requirement for concomitant other complex cardiac surgical procedures.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of left ventricular outflow tract pressure gradient reaching the standard half a year after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Major adverse cardiac events occurred within 6 months after the procedure;LVOT gradient at 72 hours after surgery and its change from baseline;Interventricular septal thickness at 6 months after surgery;Left atrial diameter;Left ventricular ejection fraction (LVEF);The NYHA cardiac function classification was evaluated at 6 months after operation;A permanent pacemaker was implanted;A second thoracotomy was performed to stop bleeding;The actual weight of myocardial resection during operation;Cardiopulmonary bypass time;Aortic cross-clamp time;Length of ICU stay;The total length of postoperative hospital stay; | — |
Countries
China
Contacts
Public ContactYin Zongtao
General Hospital of Northern Theater Command
Outcome results
None listed