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Construction and application of intervention plans for postoperative cognitive impairment in patients with colorectal cancer

Construction of an intervention program for postoperative cognitive impairment in patients with colorectal cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114692
Enrollment
Unknown
Registered
2025-12-16
Start date
2025-07-01
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative cognitive dysfunction

Interventions

Intervention group:In addition to routine care, patients received quadrant motor training from admission until two weeks after discharge.

Sponsors

Northern Jiangsu People's Hospital of Jiangsu Province
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Hospitalized patients meeting the diagnostic criteria for colorectal cancer and scheduled for curative surgery; 2.Age>=60years; 3.Preoperative MoCA score>= 26 points; 4.Preoperative hospital stay>=3days; 5.Able to walk independently on admission without obvious gait abnormalities; 6.Possess listening, speaking, reading and writing abilities, and agree to participate and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Exclusion criteria (1) Concurrent severe organic lesions of the heart, liver, kidneys, or other organs; (2) Accompanied by other malignant tumours; (3) Suffering from mental illness, or having a family history of mental illness; (4) Suffering from nervous system disorders affecting cognitive function, such as stroke or Alzheimer's disease, etc. 2.Withdrawal Criteria (1) Participants who voluntarily withdrew during the intervention; (2) Individuals who develop severe psychiatric disorders post-surgery and are unable to continue with the intervention.

Design outcomes

Primary

MeasureTime frame
Montreal Cognitive Assessment;

Secondary

MeasureTime frame
Herth Hope Index ;The Timed Up and Go Test (TUGT) and the Dual-Task Timed Up and Go Test (DTUGT) are used to assess the patient's dual-task performance.;Physiological indicators include C-reactive protein (CRP) and interleukin-6 (IL-6).;

Countries

China

Contacts

Public ContactFang Fang

Northern Jiangsu People's Hospital of Jiangsu Province

ffzyzxnokl@163.com+86 180 5106 1058

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026