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A Multimodal Study on the Effectiveness of Blood Flow Restriction Combined with Quantitative Proprioceptive Training for Early Rehabilitation after Anterior Cruciate Ligament Reconstruction

A Multimodal Study on the Effectiveness of Blood Flow Restriction Combined with Quantitative Proprioceptive Training for Early Rehabilitation after Anterior Cruciate Ligament Reconstruction

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500114674
Enrollment
Unknown
Registered
2025-12-16
Start date
2025-12-22
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior cruciate ligament reconstruction

Interventions

Test group1:Blood Flow Restriction training+regular rehabilitation
Test group2:Quantitative Proprioceptive training+Blood Flow Restriction training+regular rehabilitation

Sponsors

The 900th Hospital of Joint Logistics Support Force
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Clinical diagnosis of first-time isolated rupture of the right ACL, with injury duration <2 months, and undergoing ACL reconstruction surgery; 2. Right-handed, aged 18-40 years; 3. Surgery performed by the same group of surgeons; 4. Autologous hamstring tendon used as graft material during surgery, with the procedure performed as arthroscopic single-bundle anatomical reconstruction of the unilateral anterior cruciate ligament. Fixation method: loop plate on the femoral side combined with interference screw fixation on the tibial side; 5. There was no other ligament injury requiring surgery; 6. Postoperative routine pain management, anti-inflammatory medication, and rehabilitation therapy administered. Two weeks after surgery, the affected knee achieved extension equal to the unaffected side and active flexion reached 45°; 7. Informed consent signed.

Exclusion criteria

Exclusion criteria: 1. Does not meet diagnostic criteria; 2. Accompanied by fractures or injuries to other ligaments; 3. Accompanied by severe osteoarthritis or rheumatoid arthritis; 4. History of peripheral neurovascular diseases, coagulation disorders, or deep vein thrombosis; 5. Contraindications to MRI examination; 6. Presence of other serious diseases that prevent completion of rehabilitation training and assessment.

Design outcomes

Primary

MeasureTime frame
Clinical knee function;muscle strength;Evaluation of proprioception function and balance ability;Muscle Volume and Mass;Cartilage Structure;Multi-sensory motor cortex activation;Whole-brain functional connectivity;

Countries

China

Contacts

Public ContactQing Yin

The 900th Hospital of Joint Logistics Support Force

q301304@163.com+86 186 5099 1018

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026