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Distribution of environmental pollutants in biological samples from patients with fundus diseases and their impact on the disease

Distribution of environmental pollutants in biological samples from patients with fundus diseases and their impact on the disease

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114672
Enrollment
Unknown
Registered
2025-12-16
Start date
2025-12-22
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

RVO?wAMD?DME?Age-related cataract

Interventions

The group of patients receiving intravitreal injections:None
Blank control group:None

Sponsors

Tianjin Medical University Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
50 Years to 70 Years

Inclusion criteria

Inclusion criteria: RVO/AMD/DME Patient Group: 1. Diagnosed with macular oedema via OCT, requiring intravitreal injection; normal blood pressure, normal hepatic and renal function, normal ECG; 2. Aged 50–70 years; 3. Normal blood pressure, normal hepatic and renal function, normal ECG; 4. Normal hepatic and renal function; 5. Normal ECG; Age-related cataract patient group: 1. Diagnosed with cataract significantly impairing vision, requiring cataract surgery; 2. Aged 50–70 years; 3. Normal blood pressure/glycaemia, normal hepatic and renal function, normal ECG; 4. Normal hepatic and renal function, normal ECG; 5. Normal ECG;

Exclusion criteria

Exclusion criteria: RVO/AMD/DME patient group: 1. Concurrent severe ophthalmic conditions such as retinal detachment or vitreous haemorrhage; 2. Concurrent severe systemic diseases (e.g. hepatic or renal failure, malignant tumours); Age-related cataract group: 1. Exclusion criteria include any retinal disease, prior vitrectomy, prior glaucoma surgery, or prior laser photocoagulation. 2. Positive results in routine preoperative immunological screening (hepatitis B, HIV, syphilis) or history of infectious diseases.

Design outcomes

Primary

MeasureTime frame
Heavy metal;

Secondary

MeasureTime frame
Flame retardant;

Countries

China

Contacts

Public ContactRen Xinjun

Tianjin Medical University Eye Hospital

zlrxjrsy@126.com+86 22 8642 8838

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026