Metabolic dysfunction-associated steatotic liver disease
Conditions
Interventions
Gold Standard:Using the magnetic resonance imaging-derived proton density fat fraction (MRI-PDFF) as the gold standard:
1. The simple T2DM group (Group S0): MRI-PDFF = 17.1%.
Index test:1. Acoustic attenuation imaging (ATI)
2. MRI-PDFF
3. Controlled attenuation parameter (CAP)
4. Hepatorenal index (HRI)
Sponsors
China-Japan Union Hospital of Jilin University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: (1) Age>= 18 years old (2) Clinically diagnosed with type 2 diabetes mellitus (3) Sign the informed consent form
Exclusion criteria
Exclusion criteria: (1) Excluding specific liver diseases such as alcoholic liver disease, genotype 3 hepatitis C virus infection, autoimmune hepatitis, and hepatolenticular degeneration that can cause fatty liver. (2) Excluding drugs (tamoxifen, ethamidofurane, sodium valproate, methotrexate, glucocorticoids, etc.), total parenteral nutrition, inflammatory bowel disease, celiac disease, hypothyroidism, Cushing's syndrome, beta-lipoprotein deficiency, lipodystrophic diabetes, and Mauriac syndrome that cause fatty liver. (3) Excluding acute and chronic kidney diseases and renal failure. (4) Excluding patients who have had their gallbladder removed.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Attenuation imaging;Magnetic resonance imaging-derived proton density fat fraction;Controlled attenuation parameters;Hepatorenal index; | — |
Countries
China
Contacts
Public ContactZhixia Sun
China-Japan Union Hospital of Jilin University
Outcome results
None listed