Cognitive Impairment Combined with Intracranial Venous Thrombosis
Conditions
Interventions
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age over 18 years old, gender is not limited; 2. Inpatients diagnosed with intracranial venous sinus thrombosis according to the "Chinese Guidelines for the Diagnosis and Treatment of Intracranial Venous Thrombosis 2019" or Diagnosis and Management of Cerebral Venous Thrombosis: A Scientific Statement from the American Heart Association; 3. Cognitive impairment assessed as neuropsychological assessment: MoCA<=25 (adjusted for education level) or MMSE<=29; 4.Patients and their families voluntarily joined this study and signed the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who have been diagnosed with cognitive impairment or decline caused by the following diseases: central nervous system demyelinating disease, tumor, hydrocephalus, trauma, syphilis, AIDS, Creutzfeldt-Jakob disease, severe depression, VitB12 deficiency, and hypothyroidism; 2. Patients with acute myocardial infarction, severe coronary arteriosclerosis, and bleeding tendency (such as subarachnoid hemorrhage, cerebral hemorrhage, gastrointestinal hemorrhage, extensive retinal hemorrhage, subdural hematoma, epidural hematoma, etc.); 3. Those who have contraindications to anticoagulation or endovascular therapy; 4. Participating in other clinical drug trials; 5. Expected survival < 6 months; 6.Other conditions deemed by the investigator to be inappropriate for inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ADAS-Cog; | — |
Countries
China
Contacts
Public ContactHu Bo
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed