Physiological dependence is manifested by withdrawal symptoms and signs after drug discontinuation, such as runny nose, tearing, sweating, dilated pupils, vomiting, diarrhea, muscle pain, restlessness, anxiety, and even loss of consciousness
Conditions
Interventions
Observation group:None
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1.People who have taken Zuchamu Granules for = 15 days; 2.There was no prescription information for Zuchamu Granules in the 30 days prior to its use. 3.No history of drug abuse;
Exclusion criteria
Exclusion criteria: 1.Using other addictive drugs such as morphine, Demerol, Compound Licorice Tablets, etc. 2.Combined use of other traditional Chinese medicines containing opium shell ingredients such as Xuanlu Zixiu Keli, Qingshen Pipa Lu, Zhixuebao Pian, Zhonghong Huatan Pian, and Zhixiu Huatan Wan. 3.Combined use of sedative-hypnotic drugs such as barbiturates and benzodiazepines;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The incidence rate of ADRs caused by drug dependence;Factors influencing the incidence of adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence rate of non-drug dependence-related adverse reactions; | — |
Countries
China
Contacts
Public ContactHan Yong
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed