general anesthesia
Conditions
Interventions
Propofol Group:Propofol
Sponsors
Beijing Friendship Hospital ,Capital Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Age >= 65 years, regardless of gender; 2.American Society of Anesthesiologists (ASA) physical status classification: I-III; 3.Body Mass Index (BMI): 18.5–30 kg/m^²; 4.Scheduled for elective surgery under general anesthesia, with an estimated duration of surgery exceeding 30 minutes; 5.Voluntarily participated and provided signed informed consent;
Exclusion criteria
Exclusion criteria: 1.Patients with contraindications to general anesthesia or a history of adverse anesthesia events; 2.Patients combined with brain injury, intracranial hypertension, stroke, unstable angina, or myocardial infarction; 3.Patients with respiratory insufficiency, obstructive pulmonary disease, difficult airway, or assessed as difficult intubation (modified Mallampati class III or IV); 4.Patients with uncontrolled diabetes or hypertension; 5.Patients with a history of drug abuse, alcohol abuse, or substance dependence; 6.Patients with abuse or long-term use of anesthetic, sedative, or analgesic medications; 7.Patients with known or suspected allergy or contraindication to any component of the investigational drug or protocol-specified medications (Sufentanil Citrate Injection, Propofol Medium/Long-Chain Fat Emulsion, Remifentanil Hydrochloride for Injection, or Fospropofol Disodium for Injection); 8.Patients with a history of psychiatric disorders; 9.Patients who have participated in any drug clinical trial within 1 month prior to screening; 10.Patients deemed by the investigator to have any other factors unsuitable for trial participation;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success Rate of Anesthesia Induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hypotension During Anesthesia Induction; | — |
Countries
China
Contacts
Public ContactLiujiazi Shao
Beijing Friendship Hospital ,Capital Medical University
Outcome results
None listed