Total hip replacement
Conditions
Interventions
Group A: Ropivacaine 0.375% 40 mL + Dexamethasone 5 mg:Ultrasound-guided Fascia Iliaca Compartment Block (FICB), with 40 mL of the study drug or saline injected in a single shot under real-time ultras
Group B: Ropivacaine 0.375% 40 mL + Dexmedetomidine 1 µg/kg:Ultrasound-guided Fascia Iliaca Compartment Block (FICB), with 40 mL of the study drug or saline injected in a single shot under real-time u
Group C: Ropivacaine 0.375% 40 mL + Saline:Ultrasound-guided Fascia Iliaca Compartment Block (FICB), with 40 mL of the study drug or saline injected in a single shot under real-time ultrasound guidanc
Sponsors
Shaoxing Shangyu District Traditional Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.The age is >=65 years, gender unrestricted. 2.The patient is scheduled to undergo total hip replacement under general anesthesia or epidural anesthesia. 3.American Society of Anesthesiologists (ASA) classification I–III. 4.Preoperative cognitive function is normal, and the patient is able to correctly understand and use the pain assessment tool (VAS). 5.The patient voluntarily participates in this study and has signed an informed consent form.
Exclusion criteria
Exclusion criteria: 1.Allergic to ropivacaine, dexmedetomidine, dexamethasone, or other related medications. 2.Severe heart, liver, or kidney dysfunction, or severe respiratory diseases. 3.Preoperative central or peripheral nervous system diseases affecting pain assessment. 4.Recent use of opioids, sedatives, or corticosteroids that may affect the study results. 5.Preoperative infection, coagulation disorders, or skin lesions at the iliac fascia block site. 6.Patients who refuse to participate or are unable to cooperate with the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary outcome: Duration of analgesia (from surgery end to first PCA request);Postoperative adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain scores (NRS);Postoperative opioid consumption: Record the total amount of sufentanil used in PCA and the use of rescue analgesics within 48 hours after surgery.;Postoperative hospital stay;Patient satisfaction; | — |
Countries
China
Contacts
Public ContactXu Yang
Shaoxing Shangyu District Traditional Chinese Medicine Hospital
Outcome results
None listed