Postoperative nausea and vomiting
Conditions
Interventions
Propofol group:Induce and maintain anesthesia using propofol
Fospropofol group:Induce and maintain anesthesia using fospropofol
Sponsors
Fudan University Affiliated Obstetrics and Gynecology Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: The patient is aged 18-50 years old, with ASA class I-II, BMI 18.5-28kg/m^2, and a high risk according to the simplified Apfel risk score. The alkaline phosphatase (ALP) value is within the normal range, and the patient is scheduled to undergo gynecological laparoscopic surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: Women who are pregnant or breastfeeding; have moderate to severe abnormalities in liver and kidney function; have heart or respiratory diseases; have a history of drug abuse or alcohol dependence; have a long-term history of taking sedatives or analgesics; are allergic to the experimental drug or have contraindications.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of nausea and vomiting 6 hours after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of nausea and vomiting in the post-operative recovery room;Incidence of nausea and vomiting 24 hours after surgery; | — |
Countries
China
Contacts
Public ContactMa Li
Fudan University Affiliated Obstetrics and Gynecology Hospital
Outcome results
None listed