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Clinical Application of Carrier Screening in Complex Monogenic Disorders

Clinical Application of Carrier Screening in Complex Monogenic Disorders

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114534
Enrollment
Unknown
Registered
2025-12-15
Start date
2025-12-15
Completion date
Unknown
Last updated
2026-01-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complex and difficult single-gene diseases

Interventions

Observation group of the reproductive population:None

Sponsors

Hospital Reproductive Medicine Affiliated to ShanDong University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. People with eugenics and good child-rearing; 2. People undergoing assisted reproduction

Exclusion criteria

Exclusion criteria: 1.Patients highly suspected of having genetic diseases; 2. People with a family history of genetic diseases or an adverse history of having children due to genetic diseases

Design outcomes

Primary

MeasureTime frame
Carrier detection rate;Detection rate of high-risk couples;The implementation rate of risk notification and intervention;

Secondary

MeasureTime frame
Feasibility of screening process;Follow-up compliance;The effect of birth defect prevention and control;

Countries

China

Contacts

Public ContactYuan Gao

Hospital Reproductive Medicine Affiliated to ShanDong University

gaoyuan@sduivf.com+86 531 86569866

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026