Stroke
Conditions
Interventions
Study Group 2:rTMS+Conventional rehabilitation
Study Group 1:rTMS+Motor Imagery Training+Conventional rehabilitation
Control Group:Conventional rehabilitation
Sponsors
The First Affiliated Hospital of Dalian Medical University
Eligibility
Sex/Gender
All
Age
40 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meets the World Health Organization (WHO) diagnostic criteria for stroke and confirmed by imaging examinations; 2. First onset, unilateral stroke (lesion in the left/right cerebral hemisphere), disease duration of 1-6 months; 3. Aged 40-75 years, any gender; 4. Conscious, cognitive function acceptable (Mini-Mental State Examination score >=24), able to cooperate with interventions and assessments; 5. National Institutes of Health Stroke Scale (NIHSS) score <=15 (indicating mild to moderate neurological deficits, ensuring the patient has basic cooperation ability and rehabilitation potential); 6. Affected upper limb has passive range of motion (PROM) without significant joint contracture or pain (visual analog scale =3); 7. Signed informed consent and voluntarily participates in this study.
Exclusion criteria
Exclusion criteria: 1. Presence of rTMS contraindications (such as intracranial metal implants, history of epilepsy, severe heart disease, etc.); 2. Severe cognitive impairment (Mini-Mental State Examination score <24), psychiatric disorders, or language disorders making it impossible to cooperate with training; 3. Severe muscle atrophy, fractures, joint dislocations, or other orthopedic conditions affecting motor function in the affected limb; 4. Received other neurointervention treatments such as transcranial magnetic stimulation or electrical brain stimulation within the past 3 months; 5. Pregnant or breastfeeding women; 6. Severe liver or kidney dysfunction, infectious diseases, or other systemic diseases that may affect the study process.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-Meyer Assessment for Upper Extremity Function (FMA-UE);Resting State Power Spectral Density (PSD); | — |
Secondary
| Measure | Time frame |
|---|---|
| Self-Rating Anxiety (SAS);Barthel Index (BI);Action Research Arm Test (ARAT);Self-Rating Depression (SDS); | — |
Countries
China
Contacts
Public ContactGong Xiaoyang
The First Affiliated Hospital of Dalian Medical University
Outcome results
None listed