Perioperative anxiety
Conditions
Interventions
Trial group 1:Patients in Experimental Group 1 underwent pre - operative transcranial direct current stimulation. Anodal stimulation was applied to the left dorsolateral prefrontal cortex, and cathoda
Trial group 2:Patients in Experimental Group2 underwent pre - operative sham transcranial direct current stimulation. Anodal stimulation was applied to the left dorsolateral prefrontal cortex, and ca
Trial group 3:Patients in Experimental Group 3 underwent pre - op transcranial direct current stimulation. Anodal stimulation was applied to the left dorsolateral prefrontal cortex, and cathodal to th
Control group:Patients in the control group underwent pre - op sham transcranial direct current stimulation. Anodal stimulation was applied to the left dorsolateral prefrontal cortex, and cathodal to
Sponsors
Longyan First Affiliated Hospital of Fujian Medical University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18 - 65. 2. ASA physical status ? - ?. 3. Patients undergoing elective breast cancer surgery.
Exclusion criteria
Exclusion criteria: 1. Patients refusing to sign the consent form or unable to comprehend the questionnaire. 2. Patients with neuropsychiatric disorders or a history of such. 3. Patients with cranial or scalp injuries. 4. Patients with severe cardiovascular disease. 5. Patients with severe liver or kidney dysfunction. 6. Patients with severe respiratory disease. 7. Patients with metal implants. 8. Patients with chronic pain on long-term analgesics or psychotropic drugs (including opioids, NSAIDs, sedatives, and antidepressants). 9. Patients with severe arrhythmias or neuromuscular disorders. 10. Patients allergic to esketamine. 11. Patients with glaucoma. 12. Patients with untreated or inadequately treated hyperthyroidism.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of perioperative anxiety; | — |
Secondary
| Measure | Time frame |
|---|---|
| The incidence rate of postoperative nausea and vomiting (PONV).;Pain score;Postoperative fatigue.;Sleep quality score.;Quality of post-operative recovery;Blood indicators possibly related to perioperative anxiety (fibrinogen, PLT, MPV, PDW, hematocrit);Postoperative rescue analgesic measures;Record the duration of surgery, duration of anesthesia, volume of fluid infusion, type of surgery, recovery time, postoperative extubation time, PACU stay duration, and hospitalization time; | — |
Countries
China
Contacts
Public ContactLi Shihai
Longyan First Affiliated Hospital of Fujian Medical University
Outcome results
None listed