Intraoperative penile erection
Conditions
Interventions
control group:normal saline
Intervention Group E1:0.3mg/kg esketamine pretreatment
Intervention Group E2:0.5mg/kg esketamine pretreatment
Sponsors
Department of Anesthesiology, General Hospital of Central Theater Command of the Chinese PLA
Eligibility
Sex/Gender
Male
Age
18 Years to 69 Years
Inclusion criteria
Inclusion criteria: (1) Male; (2) Aged 18-69 years; (3) ASA of I-II; (4) Scheduled to undergo transurethral ureteroscopic surgery under general anesthesia; (5) Signed informed consent form obtained.
Exclusion criteria
Exclusion criteria: (1) Patient refusal to participate; (2) Communication barriers or inability to complete the questionnaires; (3) Participation in any other clinical trial within the past 3 months; (4) Chronic use of opioids or sedative medications; (5) History of psychiatric disorders or substance abuse; (6) History of priapism or erectile dysfunction; (7) Presence of uncontrolled cardiac, cerebral, pulmonary, hepatic, or renal dysfunction; (8) Known allergy to Esketamine or any other related drugs used in the study; (9)Patients with contraindications for the use of laryngeal mask.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the incidence of IPE;Postoperative recovery(The QoR-40 scale score); | — |
Secondary
| Measure | Time frame |
|---|---|
| heart rate;blood pressure;Erection degree(Porst scale);Irritative Bladder Symptoms;Emergence Time;Extubation Time;Riker Sedation-Agitation Scale;Dosage of narcotic drugs;Lung function(FVCFEV1MMEF);Adverse reactions and complications; | — |
Countries
China
Contacts
Public ContactXiang Zhou
General Hospital of Central Theater Command of the Chinese PLA
Outcome results
None listed