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Impact of immune checkpoint inhibitor neoadjuvant therapy on the perioperative severe complications of patients with esophageal cancer undergoing endoscopic radical surgery

Impact of immune checkpoint inhibitor neoadjuvant therapy on the perioperative severe complications of patients with esophageal cancer undergoing endoscopic radical surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114497
Enrollment
Unknown
Registered
2025-12-12
Start date
2026-01-01
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

esophagus cancer

Interventions

Non-ICI group:None
ICI group:None

Sponsors

Fudan University Zhongshan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >=18 years; 2. Complete clinical and pathological data and follow-up information; 3. Normal hematopoietic, renal, hepatic, cardiac, and pulmonary functions; 4. Underwent minimally invasive radical esophagectomy for esophageal cancer.

Exclusion criteria

Exclusion criteria: 1. Postoperative pathology shows non-esophageal adenocarcinoma or other non-squamous cell carcinoma; 2. Non-esophageal primary cancer; 3. History of other primary malignant tumors; 4. Previous atrial fibrillation or significant preoperative heart disease.

Design outcomes

Primary

MeasureTime frame
postoperative atrial fibrillation ;

Secondary

MeasureTime frame
postoperative pneumonia;postoperative ARDS;postoperative atelectasis;postoperative pleural effusion;postoperative drainage;Anastomotic leak;Wound infection;Blood transfusion;Reoperation;Hospital stay length;60 days postoperative mortility ;Surgical complications with a postoperative CD grade of 3 or higher;

Countries

China

Contacts

Public ContactWang Hao

ZhongShan Hospital Fudan University

wang.hao2@zs-hospital.sh.cn+86 135 0162 2126

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026