Type 2 Diabetes Mellitus
Conditions
Interventions
SGLT2i group:Henggliezin 10 mg/day orally
Control group:Reglidine 100 mg/day orally
Sponsors
Shanghai East Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meets the WHO or ADA diagnostic criteria for type 2 diabetes, with a disease duration of no more than 1 year; 2. BMI >= 24 kg/m^2; 3. Age range: 18-75 years; 4. Blood sugar is controlled solely through lifestyle measures, without the use of hypoglycemic drugs.
Exclusion criteria
Exclusion criteria: 1.Patients with severe hepatic or renal dysfunction; gastrointestinal disorders; or acute complications. 2.History of confirmed or suspected alcohol or drug abuse, or the presence of any other condition that, in the investigator’s judgment, would reduce the likelihood of enrollment or complicate protocol compliance. 3.Any other condition or disease that, in the opinion of the investigator, would make the subject unsuitable for participation in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body fat composition; | — |
Secondary
| Measure | Time frame |
|---|---|
| TNF-a;HBA1c;Fasting C-peptide;Lipid Profile;free fatty acid;FPG;ß-hydroxybutyrate;BDH1;IL-6;Fasting insulin;CPT-1; | — |
Countries
China
Contacts
Public ContactPeicheng Li
Shanghai East Hospital
Outcome results
None listed