Respiratory failure
Conditions
Interventions
Inteventional group:Weaning trial may be considered when FiO2 150 mmHg.
Control group:Traditional weaning methods are employed, including assessment of the underlying disease, circulatory function, oxygenation, and pulmonary function. Weaning trial may be considered if th
(2) Only minimal vasopressor support is required, such as norepinephrine dosage 150 mmHg
(4) Respiratory rate < 20 breaths per minute.
Sponsors
Cancer Hospital, Chinese Academy of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1 Patients with an expected mechanical ventilation duration exceeding 48 hours 2 Hemoglobin >= 100 g/L; 3 ALT <= 1.5 x 10^9 U/L)
Exclusion criteria
Exclusion criteria: 1 It is expected that mechanical ventilation will be required for less than 48 hours.2 It is expected to die or be discharged voluntarily within 48 hours; 3 The patient's family members do not agree to enrollment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reintubation rate at 48 hours; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation;Rate of ventilator associated pneumonia ;28-day mortality; | — |
Countries
China
Contacts
Public ContactXing Xuezhong
Cancer Hospital, Chinese Academy of Medical Sciences
Outcome results
None listed