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Construction and Clinical Validation Study of a Prediction Model for Depression After Ischemic Stroke

Construction and Validation of a Traditional Chinese and Western Medicine Prediction Model for Post-Stroke Depression

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500114473
Enrollment
Unknown
Registered
2025-12-12
Start date
2025-12-20
Completion date
Unknown
Last updated
2025-12-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-stroke depression

Interventions

Observation group:None

Sponsors

The First Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with acute ischemic stroke; 2. Admission within 7 days of symptom onset; 3. The patient and/or family members sign a written informed consent form.

Exclusion criteria

Exclusion criteria: 1. Individuals with a history of depression, schizophrenia, bipolar disorder, etc.; 2. Patients with a pre-stroke modified Rankin Scale score greater than 2; 3. Individuals unable to participate in neuropsychological examinations due to hearing impairments, lack of coordination, or neurological deficits, including severe aphasia.

Design outcomes

Primary

MeasureTime frame
The diagnosis of post-stroke depression (PSD) occurring 3 months after stroke;

Secondary

MeasureTime frame
Age;Gender;Alone;Eucation;Hypertension;Mini-Mental State Examination Score;National Institutes of Health Stroke Scale Score;Improved Barthel Index Score;Self-Rating Depression Scale Score;Hamilton Depression Rating Scale-17 Score;Total cholesterol;Triglyceride;Plasma fibrinogen;Indirect bilirubin;Alanine aminotransferase;C-reactive protein;Systemic Immune-Inflammation Index;Homocysteine;Platelet-to-lymphocyte ratio;Stroke location;Glomerular filtration rate;

Countries

China

Contacts

Public ContactMin Su

The First Affiliated Hospital of Chongqing Medical University

dycsss152@163.com+86 159 2804 0367

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026